霍克斯的遗传修饰驱动了高度多态的熊蜂熊蜂的模拟色彩模式变化
Wanhu Yang1, Jixiang Cui1, Yuxin Chen1
1Department of Entomology and MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing 100193, China.
Molecular biology and evolution
|December 1, 2023
概括
熊蜂 (Bombus breviceps) 的遗传变异控制着模仿色彩模式. 位于霍克斯基因之间的长非编码RNA可能推动了色和黑色腹部颜色的演变,揭示了模仿的独特遗传路线.
科学领域:
- 进化生物学是进化的生物学.
- 遗传学 遗传学是一种遗传学.
- 发育生物学是发展生物学.
背景情况:
- 穆勒尔模仿是适应性表型分歧和融合的关键驱动力.
- 熊蜂模仿色彩变化的遗传基础在很大程度上仍未被探索.
- 在南亚的Müllerian模仿环中,Bombus breviceps表现出多态的腹部坐标颜色 (从色到黑色).
研究的目的:
- 调查Bombus breviceps.模仿色彩模式变化的遗传基础.
- 确定负责腹部颜色变态的遗传位置和分子机制.
- 为了比较仿生物种中颜色进化的遗传路径.
主要方法:
- 基因交叉实验,以确定颜色表型的遗传模式.
- 全基因组关联研究以确定与颜色变异相关的遗传位置.
- 基因表达分析和RNA干扰,以评估特定基因和非编码RNA的作用.
- 在相关的模仿物种中对已识别的位点进行比较分析.
主要成果:
- 颜色二态性是由单个门德尔基位控制的,其中色占主导地位.
- 霍克斯基因abd-A和Abd-B之间的特定基因间区域与颜色变异密切相关.
- 在abd-A和Abd-B之间对跨基因长非编码RNA (lncRNA) 的差异表达似乎驱动了颜色差异化.
- 仿真物种利用不同的遗传途径进行相似的颜色变化,表明通过不同的机制融合进化.
结论:
- 霍克斯基因区域被确定为大黄蜂颜色模式进化的基因组热点.
- Pleitotropic 发育位点,如已识别的 lncRNA,可以促进适应性辐射.
- 熊蜂的模拟融合可以通过独立的遗传创新来实现.
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