抑郁症对中风幸存者的中风结局的影响:系统性审查和元分析
Seble Shewangizaw1, Wubalem Fekadu1, Yohannes Gebregzihabhier1,2
1WHO Collaborating Centre for Mental Health Research and Capacity Building, Department of Psychiatry, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
PloS one
|December 1, 2023
概括
抑郁症显著影响中风恢复,功能恶化和生存率. 早期诊断和干预对于改善中风后患者的治疗结果至关重要.
科学领域:
- 神经学 神经学
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 抑郁症是中风后的一个已知的并发症.
- 关于抑郁症对中风恢复的多维影响的证据有限.
- 本综述综合了目前关于抑郁症对中风结果影响的证据.
研究的目的:
- 综合审查抑郁症对各种中风结果的影响.
- 识别现有文献中的差距,特别是在低收入环境中.
- 为临床实践和未来研究方向提供信息.
主要方法:
- 从多个数据库 (PubMed,PsycINFO,EMBASE,Global Index Medicus) 来进行前性研究的系统审查.
- 包括标准集中在研究抑郁症对认知,恢复工作,生活质量,功能和生存的影响的研究上.
- 使用有效公共卫生实践项目 (EPHPP) 工具评估偏见风险.
主要成果:
- 包括80项前性研究,检查了多种类型的中风结果.
- 抑郁症始终与较差的工作回归,生活质量,功能和死亡率的增加有关.
- 抑郁症对中风后认知功能的影响是不确定的.
结论:
- 抑郁症显著影响多次中风的结果,包括生存和功能.
- 关于抑郁症对认知的影响的证据仍然没有确定性.
- 对中风幸存者进行早期抑郁症诊断和干预至关重要,特别是在代表性不足的人群中.
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