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Updated: Jul 9, 2025

Author Spotlight: Identifying Compensatory Pathways in Malaria Parasites Containing Hypomorphic Allele of Essential Protein Kinases
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凯尔奇13区间包含疟疾寄生虫中高度分离的囊泡贩运蛋白

Sabine Schmidt1, Jan Stephan Wichers-Misterek1, Hannah Michaela Behrens1

  • 1Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.

PLoS pathogens
|December 1, 2023
PubMed
概括

凯尔奇13 (K13) 蛋白中的单个氨基酸变化降低了Plasmodium falciparum寄生虫对艺术素药物的敏感性. 这项研究确定了参与宿主细胞细胞醇吸收的新的K13区块蛋白,影响药物耐药性和寄生虫入侵.

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