草甘除草剂摄入对均衡饮食的老鼠功能的影响
Bruno Reis Moreira Nacano1, Marcia Bastos Convento2, Andréia Silva de Oliveira2
1Universidade Cruzeiro do Sul, Programa de Pós-Graduação Interdisciplinar em Ciências da Saúde, São Paulo, SP, Brazil.
Jornal brasileiro de nefrologia
|December 1, 2023
概括
在老鼠中,即使饮食均衡,每日摄入草甘也会导致脏损伤,包括体重减轻和细胞变化. 这表明食品中的草甘对人类脏存在潜在风险.
科学领域:
- 环境毒理学环境毒理学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 食品安全 食品安全
背景情况:
- 草甘是一种广泛使用的除草剂,人们越来越担心其对人类健康的影响.
- 在巴西,在超加工食品中检测到草甘的残留物.
- 超加工食品的消费与慢性病风险增加有关.
研究的目的:
- 调查每日草甘摄入量对大鼠功能的影响.
- 评估草甘对脏体重,功能,损伤标志物和氧化应激的影响.
主要方法:
- 在平衡饮食的同时,每天给大鼠注射5毫克/体重千克的草甘.
- 评估功能,体重,损伤标志物 (KIM-1) 和氧化应激.
主要成果:
- 观察到脏体重的减少.
- 组织病理学分析显示,脏组织的真空化和KIM-1的上调.
- 损伤与线粒体反应性氧物种产量增加有关.
结论:
- 每日暴露于草甘,即使在均衡的饮食中,也会诱导大鼠的脏变化,这表明人类脏的潜在风险.
- 超加工食品中的草甘可能会加剧损伤.
- 强调迫切需要监管超加工食品中的草甘含量.
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