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Updated: Jul 9, 2025

Inhibitory Synapse Formation in a Co-culture Model Incorporating GABAergic Medium Spiny Neurons and HEK293 Cells Stably Expressing GABAA Receptors
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发现了选择性准螺旋2-FMN2相互作用的抑制片段

Radoslaw Kitel1, Ewa Surmiak1, Jan Borggräfe2,3

  • 1Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387 Kracow, Poland.

Journal of medicinal chemistry
|December 1, 2023
PubMed
概括

研究人员发现了针对Spire2-Formin-binding protein 2 (Spire2-FMN2) 相互作用的选择性碎片,而不是Spire1-FMN2. 化合物13是开发化学探测器的验证起点.

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