乳房扫描乳腺密度和女性心血管疾病风险
Thi Xuan Mai Tran1, Yoosoo Chang2, Soyeoun Kim1
1Department of Preventive Medicine, Hanyang University College of Medicine, Seoul, Republic of Korea.
Atherosclerosis
|December 1, 2023
概括
乳房扫描乳腺密度预测女性心血管疾病 (CVD) 事件. 将乳腺密度添加到弗雷明汉风险评分 (FRS) 中可以改善心血管疾病风险预测,特别是在低风险人群中.
科学领域:
- 心脏病学 心脏病学
- 放射学 放射学是一门学科.
- 流行病学 流行病学
背景情况:
- 心血管疾病 (CVD) 是妇女死亡的主要原因.
- 乳房扫描乳腺密度是乳腺癌的已知危险因素.
- 乳腺密度与心血管疾病风险之间的关联尚未完全理解.
研究的目的:
- 为了评估乳房扫描乳腺密度对女性随后心血管疾病事件的预测作用.
- 评估将乳腺密度添加到Framingham风险评分 (FRS) 中是否可以改善心血管疾病风险预测.
主要方法:
- 一项大规模的队列研究,包括4,268,579名年龄≥40岁的女性接受乳房扫描查.
- 乳腺密度使用乳腺成像报告和数据系统 (BI-RADS) 分类.
- 结局包括冠心病,脑血管疾病,外围动脉疾病和心力衰竭,随访持续到2020年.
主要成果:
- 乳腺密度较低的类别与患心血管疾病的风险较高有关.
- 乳房几乎完全肥胖的女性与乳房非常密集的女性相比,心血管疾病风险高29%.
- 将乳腺密度添加到FRS模型中略有改善了心血管疾病风险预测,特别是在低风险女性中.
结论:
- 乳房扫描乳腺密度是女性发生心血管疾病的独立预测因素.
- 将乳腺密度纳入风险评估模型可以提高心血管疾病预测的准确性.
- 这一发现特别适用于在低风险人群中完善风险分层.
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