骨组织物质参数识别的双层elasto-visco-plastic风湿学模型由损害法扩展到一个损害法
Andreas G Reisinger1, Martin Bittner-Frank1, Philipp J Thurner2
1Department of Anatomy and Biomechanics, Karl Landsteiner University of Health Sciences, Austria; Institute of Lightweight Design and Structural Biomechanics, Vienna University of Technology, Austria.
Journal of the mechanical behavior of biomedical materials
|December 1, 2023
概括
这项研究使用反向风湿学建模量化了骨组织损伤. 新的损伤模型准确地捕捉了机械负荷下人类尾骨的刚度降低.
科学领域:
- 生物力学 生物力学
- 材料科学 材料科学 材料科学
- 整形外科 整形外科 整形外科
背景情况:
- 骨组织对机械负荷表现出复杂的反应,包括硬化,粘度和损伤.
- 量化这些机械性质对于理解骨疾病和生物机械临床试验至关重要.
研究的目的:
- 通过逆流学建模,在循环超载下量化单个湿的人类轨道的损伤增长.
- 用损害法来扩展现有的风学材料模型,并验证其性能.
主要方法:
- 一个现有的风学材料模型 (线性弹性,可塑性,粘度) 通过损害法得到了增强.
- 扩展模型被用于优化过程中,以识别材料参数和在拉力负荷下的人类轨道骨的损伤增长.
- 模型适合测试数据的情况与没有损坏的模型进行了比较.
主要成果:
- 损坏模型改善了数据的拟合,与无损坏模型 (3.03 MPa) 相比,平均RMSE (2.52 MPa) 较低.
- 损伤模型在负载历史上有质地表示了刚度的降低,为潮湿的人类椎骨提供了现实的即时 (11.92 GPa) 和长期 (5.73 GPa) 模块.
- 观察到显著的损伤增长,值超过0.8接近故障,每周期的相对刚度损失与文献一致.
结论:
- 反向风湿学建模对于从单个机械测量中量化复杂的构成性行为是有效的.
- 开发的损伤模型准确地代表了骨组织的损伤演变,将其与其他机械影响分开.
- 这种方法可以在整个加载历史中持续识别损坏的进展.
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