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Updated: Jul 9, 2025

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合成GPR40/FFAR1激动剂:对最新的化学类及其结构-活性关系进行了详尽的调查

Abhik Paul1, Sourin Nahar1, Pankaj Nahata1

  • 1Department of Pharmaceutical Technology, Jadavpur University, West Bengal, Kolkata, 700 032, India.

European journal of medicinal chemistry
|December 1, 2023
PubMed
概括

研究人员正在开发针对自由脂肪酸受体1 (FFAR1或GPR40) 的新型合成激动剂,以改善2型糖尿病治疗. 本综述强调了GPR40/FFAR1激动剂设计的最新进展,以提高有效性和安全性.

关键词:
化学-生物相互作用.自由脂肪酸受体1 自由脂肪酸受体1作为GPR40激动剂的使用者.结构与活动之间的关系.2型糖尿病是什么? 2型糖尿病是什么?

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