在患有桃体切除术后出血的儿科患者中,桃体微生物组因桃体缩而发生出血
Bo Duan1, Mingyu Gan2, Zhengmin Xu1
1Department of Otolaryngology-Head and Neck Surgery, Children's Hospital of Fudan University, 399 Wanyuan Road, Minhang District, Shanghai, 201102, China.
International journal of pediatric otorhinolaryngology
|December 1, 2023
概括
改变的桃体微生物群,特别是增加的Neisseria,Capnocytophaga和Veillonella,可能会导致桃体切除术后的出血 (PTH). 这一发现为预防桃体切除术后出血提供了新的途径.
科学领域:
- 微生物学 微生物学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 基因组学就是基因组学.
背景情况:
- 桃体切除术后出血 (PTH) 是一个常见的并发症.
- 桃体微生物群在PTH发育中的作用尚不清楚.
研究的目的:
- 为了比较带有和没有PTH的患者之间的桃体微生物群.
- 为了识别与PTH相关的特定微生物特征.
主要方法:
- 来自19名PTH患者和21名对照者的桃体组织的元基因组测序.
- 使用PCoA和NMDS对α和β多样性的分析.
- 使用LDA分析识别差异丰富的属.
主要成果:
- 微生物丰富度或均性 (α多样性) 没有显著差异.
- 群体之间微生物群体组成 (β多样性) 的显著差异.
- 在PTH患者中增加了Neisseria,Capnocytophaga和Veillonella的丰度.
结论:
- 桃体微生物群的组成在PTH和对照组之间有所不同.
- 尼塞利亚菌,Capnocytophaga和Veillonella是PTH的潜在贡献者.
- 结果可能会为预防和治疗PTH提供新的策略.
相关概念视频
Chronic Pharyngitis
2.4K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
2.4K
Tonsillitis II: Management
114
This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
114
Tonsillitis I: Introduction
269
Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
Etiology
Three primary contributing factors have been identified.
269
Suctioning the Nasopharyngeal Airway
445
Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
Equipment Required
Equipment Required
445
Acute Pharyngitis
721
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
721


