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Updated: Jul 9, 2025

In Silico Modeling Method for Computational Aquatic Toxicology of Endocrine Disruptors: A Software-Based Approach Using QSAR Toolbox
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In Silico Modeling Method for Computational Aquatic Toxicology of Endocrine Disruptors: A Software-Based Approach Using QSAR Toolbox

Published on: August 28, 2019

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双甲替代品抑制人类和老鼠的芳香酶活性:QSAR结构-活性关系和in silico对接分析

Miaomiao Xia1, Jingyi Zheng2, Sailin Chen2

  • 1Department of Gynecology and Obstetrics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China; Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital and Yuying Children's Hospital, Key Laboratory of Pediatric Anesthesiology, Ministry of Education, Key Laboratory of Anesthesiology of Zhejiang Province, Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
|December 1, 2023
PubMed
概括

双甲 (BPA) 替代品可以抑制人类和老鼠的芳酶 (CYP19A1),影响雌醇的产生. 它们的抑制强度与脂性和基大小有关.

关键词:
芳香酶是一种芳香酶.双醇是一种双醇.对接分析对接分析人类胎盘胎盘时间LogP 时间LogP

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