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Updated: Jun 17, 2026

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标准化测试用于监测血液癌症中药物敏感性的标准化测试

Pilar Ayuda-Durán1,2, Johanne U Hermansen3,4, Mariaserena Giliberto3,4

  • 1Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.

Cell death discovery
|December 1, 2023
PubMed
概括

针对AML,CLL和MM等血液癌症的优化药物敏感性测试协议提高了ex vivo准确性. 这些经过验证的方法有助于实时治疗指导和标准化,以获得更好的患者结果.

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Therapeutic Drug Monitoring: Overview and Classification01:16

Therapeutic Drug Monitoring: Overview and Classification

Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood at designated intervals to ensure the drug concentration stays within a therapeutic range. This monitoring is crucial for optimizing individual dosage regimens, enhancing therapeutic efficacy, and minimizing drug-related toxicity. TDM is vital for drugs with narrow therapeutic windows, significant variability in pharmacokinetics, and a clear correlation between plasma levels and...
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Therapeutic Drug Monitoring: Drug Analysis Methods

Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood or body tissues to tailor drug therapy effectively. This monitoring is critical for managing drugs with narrow therapeutic indices like digoxin and phenytoin, ensuring they are both safe and effective. For instance, monitoring theophylline levels in asthma patients involves precision and sensitivity to adjust doses according to individual responses to therapy, ensuring efficacy and...