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Updated: Jul 9, 2025

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
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Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

Published on: July 25, 2020

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在三阴性乳腺癌中,AURKAIP1通过稳定DDX5激活瘤进展

Wenwen Tian1,2, Yuhui Tang1, Yongzhou Luo1

  • 1Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, 651 East Dongfeng Road, Guangzhou, 510060, China.

Cell death & disease
|December 1, 2023
PubMed
概括

极光-A激酶相互作用蛋白1 (AURKAIP1) 在三阴性乳腺癌 (TNBC) 中被上调,促进了扩散和迁移. AURKAIP1针对DDX5,激活Wnt/β-catenin信号传输,并表明其作为治疗点的潜力.

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Through the Looking Glass: Time-lapse Microscopy and Longitudinal Tracking of Single Cells to Study Anti-cancer Therapeutics06:00

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