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Updated: Jul 9, 2025

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左心房和左心室的体积和功能的变化,通过三维动态心脏模型测量出心脏衰竭的患者

Yi Zhang¹, Shen-Yi Li², Tian-Tian Lu¹

¹Department of Ultrasonography, The People's Hospital of Hunan Province (The First Affiliated Hospital of Hunan Normal University), No. 61 Jiefang West Road, Changsha, 410005, China.

The international journal of cardiovascular imaging

|December 1, 2023

概括

通过保留喷射分数 (HFpEF) 诊断心力衰竭是一项挑战. 三维动态心脏建模 (3D-DHM) 揭示了HFpEF患者和健康个体之间的心脏功能显著差异,为心肌力学提供了更好的洞察力.

科学领域:

心脏病学心脏病学
生物医学工程生物医学工程
医疗成像医学成像

背景情况:

精确诊断心力衰竭与保存的喷射分数 (HFpEF) 仍然是一个临床挑战.
传统的心声回声学可能无法完全捕捉HFpEF中的复杂的心脏结构和功能变化.

研究的目的:

使用3D-DHM对HFpEF患者和健康对照者之间的心脏结构和功能进行比较.
在HFpEF患者中评估二维 (2D) 和三维 (3D) 心脏功能参数之间的差异.

主要方法:

使用3D-DHM和传统的2D方法进行心声学.
在HFpEF患者和对照组中测量左心房和心室体积和功能参数.

主要成果:

在HFpEF患者和对照组之间发现了3D心脏功能指数 (例如LVESV,3D-LVEF,ESL,SV,CI,EDmass,LAVmax,LAVmin,LAEF,LAVI) 的显著差异 (P <0.05).
没有观察到LVEDV和EDL的显著差异 (P > 0.05).
虽然2D-LVEF在对照组中没有显著差异,但与2D-LVEF相比,HFpEF患者的3D-LVEF较低 (P <0.05),表明缩功能受损.

结论:

与传统的2D方法相比,3D-DHM技术提供了更全面的心肌力学信息.
3D-DHM可以通过揭示微妙的心脏功能变化来帮助准确诊断和评估HFpEF.

关键词:

动态的心脏模型.喷射分数的喷射分数是什么心力衰竭与保存的喷射分数的心脏衰竭三维心脏功能三维心脏功能

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Pathophysiology of Heart Failure

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Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...