怀孕期间的头痛以及随后中风的风险
Ki-Woong Nam1,2, Sungyeon Ha3, Min-Jeong Oh4
1Department of Neurology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea.
The journal of headache and pain
|December 1, 2023
概括
怀孕期间的头痛 (G-HA) 会增加分娩后中风的风险. 然而,怀孕前头痛的病史可能会减少G-HA和缺血性中风之间的联系.
科学领域:
- 神经学 神经学
- 产科 产科 产科 产科 产科
- 流行病学 流行病学
背景情况:
- 初级头痛疾病是女性中风风险因素之一.
- 怀孕期间的头痛 (G-HA) 尽管在怀孕早期出现典型的改善,但仍可能发生.
- G-HA对分娩后中风风险的影响尚不清楚.
研究的目的:
- 调查怀孕期间头痛 (G-HA) 与分娩后中风风险之间的关联.
- 为了确定G-HA是否影响特定类型的中风风险,包括缺血性和出血性中风.
主要方法:
- 利用韩国国家医疗保险服务数据库对2012-2013年间分娩的妇女进行了分析.
- 定义G-HA是怀孕期间诊断的头痛.
- 从分娩到2020年12月31日追踪中风发生情况,使用ICD-10-CM代码.
主要成果:
- 在906,187名孕妇中,G-HA在6.3%的孕妇中被发现.
- 患有G-HA的女性患任何类型的中风 (aHR=1.59),缺血性中风 (aHR=1.50) 和出血性中风 (aHR=1.63) 的风险显著增加.
- G-HA与出血性中风有显著的关联,但这种关联在先前有头痛史的女性中,对于缺血性中风而言是缓解的.
结论:
- 怀孕期间的头痛与分娩后中风风险增加有关.
- G-HA与缺血性中风风险之间的关联受到怀孕前头痛疾病史的缓解.
- G-HA是产后中风的潜在危险因素,需要进一步调查.
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