2015年至2022年,与细胞外囊相关的CRISPR相关技术的全球研究趋势:2015年至2022年:一项书法测量,动态和可视化研究
Jianjing Lin1, Shicheng Jia1,2, Zilu Jiao1
1Department of Sports Medicine and Rehabilitation, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China.
Cellular & molecular biology letters
|December 1, 2023
概括
这项图书统计研究可视化了从2015年到2022年集群定期间隔的短时间palindromic重复 (CRISPR) 技术和细胞外囊泡的趋势. 它确定了未来科学探索的关键研究领域和新兴热点.
科学领域:
- 生物技术是生物技术.
- 遗传学 是一个遗传学.
- 分子生物学分子生物学
背景情况:
- 细胞外囊泡 (EVs) 越来越多地被认为是它们在细胞间通信中的作用.
- 聚类正规间隔短平行体重复 (CRISPR) 技术提供了精确的基因组编辑能力.
- 克里斯普和EV之间的协同作用提供了新的治疗和诊断机会.
研究的目的:
- 进行对与细胞外囊泡相关的CRISPR技术研究的文献分析.
- 确定过去七年 (2015-2022) 在该领域的新兴趋势,动态发展和研究热点.
- 为了可视化研究格局,并预测未来的方向.
主要方法:
- 从科学网络核心集合 (2015-2022) 收集了219篇相关文章.
- 使用R语言,VOSviewer,CiteSpace和GraphpadPrism进行文献计量分析.
- 分析出版历史,一般特征,关键词和合作,以绘制研究趋势.
主要成果:
- 出版物输出显示了持续的年度增长.
- 中国,美国和德国是主要的贡献者,英国RLUK研究图书馆提供了最多的文献.
- 关键的研究集群包括外体,纳米纤维,基因编辑,基因疗法和癌症疗法,以及基因组和蛋白质输送等新兴主题.
结论:
- 这项研究提供了2015-2022年CRISPR-EV研究的第一个文献统计概述.
- 一个知识地图突出显示当前的趋势,并确定潜在的未来研究热点.
- 这些发现为研究人员在这个快速发展的领域中提供了宝贵的见解.
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