不利的童年经历和自闭症:一个元分析
Gemma Hartley1, Fuschia Sirois1,2, Jack Purrington1
1University of Sheffield, UK.
Trauma, violence & abuse
|December 2, 2023
概括
与非自闭症同龄人相比,自闭症个体面临的不良童年经历 (ACE) 风险是双倍的. 这一元分析证实了显著的关联,强调了针对自闭症儿童和家庭的有针对性的支持和预防策略的需要.
科学领域:
- 神经发育障碍 神经发育障碍
- 儿童心理学 儿童心理学
- 公共卫生 公共卫生
背景情况:
- 自闭症谱系障碍 (ASD) 是一种神经发育状况.
- 儿童不良经历 (ACE) 是潜在的创伤性事件.
- 以前的研究表明ASD和ACE之间存在联系.
研究的目的:
- 量化评估自闭症和ACE之间的关联.
- 通过元分析来综合现有证据.
- 为了确定自闭症患者ACE的整体风险.
主要方法:
- 在八个数据库和谷歌学者中系统地搜索文献.
- 包括40项研究,超过560万参与者.
- 随机效应元分析来计算自闭症和ACE的几率比率 (OR).
主要成果:
- 自闭症患者经历ACE的平均OR为2.11 (CI为1.61,2.77).
- 根据ACE类型,比较组和人群观察到显著的异质性.
- 中等确定性证据表明自闭症个体的风险较高.
结论:
- 自闭症患者患有ACE的风险明显更高.
- 这些发现强调了预防性干预和支持系统的必要性.
- 解决ACE对于自闭症患者及其家属的福祉至关重要.
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