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轨道减压对导管,循环扭转和双眼视的影响
Hinke Marijke Jellema1, Martina Althaus2, Elly Merckel-Timmer3
1Department of Ophthalmology, Amsterdam UMC Locatie AMC, Amsterdam, The Netherlands h.m.jellema@amsterdamumc.nl.
The British journal of ophthalmology
|December 2, 2023
概括
对于Graves的轨道减压.
科学领域:
- 眼科,内分泌学和整体外科
- 眼科医生 眼科 眼科
- 内分泌学 在内分泌学.
背景情况:
- 格雷夫斯轨道病 (GO) 是一种自身免疫性疾病,影响眼睛肌肉和组织.
- 轨道减压手术是对GO患者的proptosis (眼睛凸起) 的常见治疗方法.
- 在轨道减压后出现新发常态双眼 (双视) 的发生在报告的文献中有所不同.
研究的目的:
- 为了评估眼睛肌肉运动 (引) 的变化,眼睛旋转 (循环偏离),眼睛的位置,以及轨道减压后的双眼视的严重程度.
- 评估Graves轨道病症患者在轨道减压后新出现的恒定双眼视的发生率.
- 为了确定在手术后发展新发常态双眼的预测因素.
主要方法:
- 从2016年1月至2020年7月期间接受轨道减压的156名患者 (281只眼睛/轨道) 的数据的回顾性分析.
- 收集的数据包括使用戈尔曼分数的减压类型,眼睛位置,导管范围,循环偏差和双眼视的严重程度.
- 进行统计分析以评估变化和预测值.
主要成果:
- 轨道去压缩减少了proptosis的发生. 水平和垂直导管范围略有下降,但没有临床意义.
- 水平偏差转向eos偏差,而垂直偏差保持稳定. 循环扭转在主要位置和向下看的位置转向循环偏差.
- 在22%的患者中,双眼视改善了,而11%的患者患上了新发常态双眼视. 手术前限制升高 (<19°) 预测了新发的双眼视 (AUC=0.812).
结论:
- 在11%的格雷夫斯轨道病患者中,轨道压缩可以导致新发常态双眼,尽管22%的患者经历了改善.
- 观察到的导管和偏差的变化具有统计学意义,但没有临床意义.
- 手术前受限升高 (<19°) 的患者有较高的新发常态双眼视的风险,手术前的循环偏差可能会在手术后恶化.
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