在COVID-19患者中妄想的特征
Bratislavske lekarske listy
|December 2, 2023
概括
痴呆症影响了斯洛伐克近30%的住院COVID-19患者. 某些治疗和精神症状与妄想有关,影响住院时间,但不影响死亡率.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 精神病学是一个精神病学.
背景情况:
- 由SARS-CoV-2引起的COVID-19大流行导致全球健康面临重大挑战.
- Delirium 是一种急性脑功能障碍的关键形式,经常在住院患者中观察到,包括那些患有COVID-19的患者.
研究的目的:
- 确定斯洛伐克住院COVID-19患者中痴呆症的发生率.
- 为了调查痴呆症,精神症状和各种治疗方式之间的关联.
- 检查 Delirium 对住院时间和患者死亡率的影响.
主要方法:
- 一项对474名在斯洛伐克科西切确认感染SARS-CoV-2的住院患者的回顾性分析.
- 根据标准化的ICD-10标准进行 Delirium 诊断.
- 统计分析,以探索妄,精神症状,治疗和临床结果之间的相关性.
主要成果:
- 在29.54%的患者 (140个人) 中诊断出 Delirium.
- 在 Delirium 患者中观察到更高的失眠,焦虑,昏昏欲睡,兴奋和侵略率.
- 包括高流量鼻氧,葡萄糖皮质类药物,抗生素和anakinra在内的治疗与 Delirium 发病率的增加有关. 抗精神病药物如蒂亚普里德,奎蒂阿平和哈洛佩里多尔与妄想相关,而西塔洛普拉姆则显示出潜在的保护作用. bensodiazepines,催眠药,或 tiapride 与更长的住院时间有关. 没有发现与死亡率有显著关联.
结论:
- 痴呆症是斯洛伐克COVID-19患者的一个重大问题,影响了近30%的住院患者.
- 特定的治疗方法和精神症状的存在与妄想发病率和住院时间有关.
- 精心管理精神症状和明智选择治疗方法对于优化COVID-19患者的治疗结果至关重要.
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