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拥有猫和与精神分裂症相关的疾病和精神病类似的经历:系统性审查和元分析
John J McGrath1,2,3, Carmen C W Lim2, Sukanta Saha2
1Queensland Brain Institute, University of Queensland, St Lucia, QLD, Australia.
Schizophrenia bulletin
|December 2, 2023
概括
猫拥有与精神分裂症相关疾病的风险更高有关,根据系统性审查和元分析. 需要进一步进行高质量的研究来证实这些发现,并探索类似精神病的经历.
科学领域:
- 精神病学和心理健康 精神病学和心理健康
- 流行病学 流行病学
- 环境健康 环境健康
背景情况:
- 拥有猫被假设为精神分裂症和相关疾病的潜在风险改变因素.
- 以前的研究表明,与猫接触和精神病类似经历 (PLE) 之间可能存在关联.
研究的目的:
- 系统地审查和对现有的关于猫养猫与精神分裂症相关结果关系的文献进行元分析.
- 量化猫暴露和患上精神分裂症相关疾病的风险之间的关联.
主要方法:
- 在多个数据库 (Medline,Embase,CINAHL,Web of Science) 和灰色文献中进行了全面的搜索.
- 包括报告关于拥有猫和精神分裂症相关结果的原始数据的研究,并使用随机效应模型进行了元分析.
- 评估了偏差风险,异质性和研究质量,以确保可靠的研究结果.
主要成果:
- 包含的17项研究的元分析显示,大致定义的猫拥有与精神分裂症相关疾病的几率增加之间存在显著的关联.
- 聚合未调整的赔率比率从1.56到2.14不等,聚合调整的赔率比率从2.40到2.44不等.
- 与精神病类似体验 (PLE) 的关联是不确定的,因为结果措施的异质性.
结论:
- 这些发现支持了猫暴露与精神分裂症相关疾病风险增加有关的假设.
- 关于精神病类经历的证据仍然是混合的,强调需要更严格的研究.
- 建议进行进一步的高质量研究,以阐明猫养猫与心理健康结果之间的复杂关系.
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