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Updated: Jul 9, 2025

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IRX2通过转录抑制RUVBL1来调节子宫内膜癌瘤发生

Qinyang Xu1, Wanzhen Zhou1, Yuedi Zhou1

  • 1Department of Gynecology and Obstetrics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Experimental cell research
|December 2, 2023
PubMed
概括

由DNA甲基化驱动的Iroquois Homeobox 2 (IRX2) 表达的减少,促进子宫内膜癌 (EC) 的生长. 恢复IRX2可以抑制瘤的进展,并向RUVBL1通路,提供一种潜在的EC治疗策略.

关键词:
宫内膜癌 (Endometrial carcinoma) 是一种子宫内膜癌.在IRX2中,IRX2是IRX2.瘤发生的发生因子.在RUVBL1中,RUVBL1是RUVBL1.幸存的生存方式

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