细胞减小手术后与静脉关闭相关的因素
Marianna Maspero1, Sumeyye Yilmaz1, Daniel Joyce2
1Department of Colon and Rectal Surgery, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH, USA.
通过高热性腹腔内化疗 (HIPEC) 进行细胞还原性手术 (CRS) 后的口腔逆转在74%的患者中是可以实现的. 低级/中级瘤是成功关口的最强有力的预测因素.
科学领域:
- 手术瘤学手术瘤学
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
背景情况:
- 在带或不带高热性腹腔内化疗 (HIPEC) 的细胞还原性手术 (CRS) 后,口腔闭塞率通常很低.
- 成功逆转口腔的预测因素需要进一步的研究.
研究的目的:
- 为了确定在接受CRS治疗的患者中,暂时性静脉瘤的静脉瘤逆转的预测因子.
主要方法:
- 在2009年至2021年期间,对接受了临时骨髓切除术的CRS患者进行了回顾性分析.
- 患者特征和结局的比较,对象分别是胃口逆转患者和没有胃口逆转患者.
主要成果:
- 在625次CRS手术中,有72名患者 (11.5%) 符合纳入标准;有74% (53名患者) 实现了口腔闭塞.
- 与门逆转相关的因素包括较低的瘤等级,尾粘膜性瘤和循环静脉切除术.
- 疾病进展或死亡是不逆转的最常见原因 (74%的病例).
- 多变量分析确定了低级/中级瘤分化作为静脉关闭的重要预测因素.
结论:
- 在这组接受CRS的患者中,观察到74%的静脉关闭率,这些患者有临时性静脉.
- 低级/中级瘤差异化是成功逆转静脉口腔的最强有力的预测因素.
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