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时钟基因Bmal1控制了类风湿性关节炎纤维细胞样同胞细胞中的炎症媒介

Kenta Kaneshiro1, Kanako Nakagawa1, Hikari Tsukamoto1

  • 1Department of Biophysics, Kobe University Graduate School of Health Sciences, Kobe, Japan.

Biochemical and biophysical research communications
|December 3, 2023
PubMed
概括

主钟基因Bmal1 (大脑和肌肉ARNT类蛋白1) 通过调节炎症介质,在类风湿性关节炎 (RA) 中发挥作用. 沉默Bmal1降低了RA-纤维细胞样同胞细胞 (RA-FLS) 中关键炎症分子的产生.

关键词:
在 BMAL1 中,时钟基因 时钟基因纤维细胞类同胞细胞类似于纤维细胞.炎症调解剂是一种炎症调解剂.类风湿性关节炎 类风湿性关节炎 类风湿性关节炎

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