一种新的气体栓塞疗法,使用微气泡电凝治疗癌症
Hossein Azizi Sormoli1, Afsaneh Mojra2, Ghassem Heidarinejad1
1Department of Mechanical Engineering, Tarbiat Modares University, Tehran, Iran.
Computer methods and programs in biomedicine
|December 3, 2023
概括
这项研究引入了一种新的气体栓塞疗法,使用电场来控制癌症治疗的微泡,克服了当前方法的局限性. 这种方法精确地准瘤,并考虑到高间歇性液压,提供了一种新的非侵入性治疗方法.
科学领域:
- 生物医学工程 生物医学工程
- 计算流体动力学的流体动力学.
- 在瘤学瘤学.
背景情况:
- 栓塞疗法用于瘤生长中断,但面临着有限的访问和控制等挑战.
- 现有的方法不能充分解决瘤特征,如高间歇性流体压力.
研究的目的:
- 通过瘤血管封闭,在癌症治疗中引入一种新的气体栓塞疗法的数值方法.
- 开发一种使用电场精确控制微气泡栓塞的方法.
主要方法:
- 从Levovist注射到瘤微血管中产生的气体微泡.
- 通过对瘤食器施加电场来控制微气泡的运动.
- 开发了一种完全合的模型,包括相场,卡罗,纳维尔-斯托克斯和麦克斯韦应力张量,并结合了间歇性流体压力.
主要成果:
- 微气泡的变形和移位率随着应用的电势而增加.
- 微气泡壁粘附所需的时间随着电压的增加 (1.97ms到22μs) 显著减少.
- 一个12.5V电位诱导的微泡凝聚和气柱形成阻碍了血液流动.
结论:
- 这种新型的栓塞程序提供了一种非侵入性,向性癌症治疗,通过电场精确控制阻断器的大小.
- 这种方法显示了逐步治疗晚期癌症的潜力,解决瘤耐药性和复发.
相关概念视频
02:49Cancer Therapies
7.7K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.7K
01:15Drugs that Stabilize Microtubules
2.1K
Microtubules are dynamic structures that undergo cycles of catastrophe and rescue. The microtubules play a central role in cell division by forming the spindle apparatus for segregating the chromosomes. This makes them ideal targets for regulating dividing cells in tumors and malignant cancer cells. Microtubule stabilizing drugs help stabilize the microtubule formation and promote its polymerization. Paclitaxel was the first microtubule stabilizing agent used as anticancer drug in chemotherapy...
2.1K