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Updated: Jul 9, 2025

Integration of Bioinformatics Approaches and Experimental Validations to Understand the Role of Notch Signaling in Ovarian Cancer
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Published on: January 12, 2020

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在活细胞中对基蛋白NOTCH1的近距离依赖核相互作用的全面分析

Haydee M Torres1, Fang Fang2, Danielle G May3

  • 1Cancer Biology & Immunotherapies Group, Sanford Research, Sioux Falls, South Dakota, USA; Department of Chemistry and Biochemistry, South Dakota State University, Brookings, South Dakota, USA.

The Journal of biological chemistry
|December 3, 2023
PubMed
概括

研究人员使用靠近依赖生物识别来探索Notch1coprotein的核相互作用. 这项研究揭示了新的蛋白质关联,对于理解癌症中的Notch信号和识别新的治疗点至关重要.

关键词:
生物ID BioID 是一个生物ID.在 HDAC1 中,HDAC1 是在NICD中,NICD是指NICD.在NOTCH1中,口路径是一个口路径.蛋白质组学是指蛋白质组学.癌症 癌症 癌症 癌症 癌症网络分析 网络分析蛋白质与蛋白质的相互作用

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