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血液培养时间与阳性,死亡率和细菌性病的严重程度之间的关系

N Deguchi¹, K Ishikawa¹, S Tokioka²

¹Department of Infectious Diseases, St. Luke's International Hospital, Tokyo, Japan.

Infectious diseases now

|December 3, 2023

概括

对于黄金杆菌菌菌,在24小时内较长的阳性时间 (TTP) 与30天死亡率的增加有关. 对其他常见病原体的TTP显示没有显著的死亡率相关性.

科学领域:

医学微生物学医学微生物学
传染性疾病传染性疾病
临床病理学临床病理学

背景情况:

血液培养中的时间到阳性 (TTP) 表明细菌生长速度.
了解TTP与患者结局的关联对于管理细菌血症至关重要.

研究的目的:

调查TTP与细菌病患者的严重程度或死亡率之间的关系.
为了确定TTP是否预测特定细菌病原体的死亡率.

主要方法:

进行了一项单一中心的回顾性研究.
包括具有阳性血液培养结果的患者.

主要成果:

较长的TTP与Staphylococcus aureus细菌病的30天死亡率相关 (17.4h与14.1h).
当TTP超过24小时时,S. aureus的死亡风险显著增加 (p=0.04).
对于Streptococcus pneumoniae,Enterococcus sp.,Enterobacteriaceae和Candida sp.的TTP,我们可以使用这些类型. 与死亡率没有显著关联.

结论:

超过24小时的TTP是30天死亡率的显著预测因素,特别是对于黄金杆菌菌菌的死亡率.
对于由其他几种常见病原体引起的细菌病,TTP不是可靠的死亡率预测指标.

关键词:

细菌病是什么意思细菌病是什么意思血液培养血液培养是什么?死亡率死亡率死亡率黄金葡萄球菌黄金葡萄球菌现在是积极的时间了.

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