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Updated: Jul 9, 2025

A Simplified System for Evaluating Cell Mechanosensing and Durotaxis In Vitro
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通过皮埃佐1调节平滑肌细胞体积,以应对增强的细胞外矩阵刚度

Robert T Johnson1, Reesha Solanki1, Finn Wostear1

  • 1School of Pharmacy, University of East Anglia, Norwich, UK.

British journal of pharmacology
|December 3, 2023
PubMed
概括

血管光滑肌细胞 (VSMC) 的体积通过Piezo1/PKC/aquaporin-1通路在刚性矩阵上增加. 针对这种途径可以增强VSMC对矩阵刚性的反应,而不会影响收缩性.

关键词:
这种水族-1-1.细胞体积细胞体积的细胞体积.矩阵的刚性 矩阵的刚性一个Piezo,一个Piezo.血管光滑肌肉的肌肉.

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