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一个合成细胞毒性T细胞平台,用于快速原型化TCR功能

Govinda Sharma1, James Round1, Fei Teng1

  • 1Michael Smith Genome Sciences Centre; British Columbia Cancer Research Institute; 675 W 10 Ave, Vancouver, BC, V5Z 1L3; Canada.

bioRxiv : the preprint server for biology
|December 4, 2023
PubMed
概括

研究人员开发了一个新的平台来测试T细胞受体 (TCR) 功能,从而能够精确测量细胞毒性潜力和交叉反应性. 该工具有助于优化治疗TCR,以提高疗效和减少非目标效应.

关键词:
T细胞受体受体的 T 细胞受体.适应性免疫是一种适应性免疫.生物平台 生物平台癌症免疫疗法免疫疗法细胞工程 细胞工程高通量选的高通量选合成生物学 合成生物学

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