在转移性乳腺癌中进行全食,植物性随机对照试验:可行性,营养和患者报告的结果
Erin K Campbell1, Thomas M Campbell1, Eva Culakova1
1University of Rochester Medical Center.
Research square
|December 4, 2023
概括
一种全食,植物性 (WFPB) 饮食干预改善了转移性乳腺癌 (MBC) 的女性的生活质量 (QOL). 这种饮食方法增强了认知功能和情绪健康,同时减少了疲劳.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 生活质量研究 研究 生命质量研究
背景情况:
- 生活质量 (QOL) 是转移性乳腺癌 (MBC) 患者的关键结果,受认知障碍,疲劳和体重增加显著影响.
- 评估饮食干预措施对MBC患者的QOL的可行性和影响对于支持性护理至关重要.
研究的目的:
- 评估一种全食,植物性 (WFPB) 饮食干预措施的可行性,旨在促进MBC妇女的体重减轻.
- 评估WFPB饮食在这个患者群体中改善QOL的潜力.
主要方法:
- 一项随机对照试验以2:1分配比分配给患有MBC的妇女,接受WFPB饮食干预 (n=21) 或常规护理 (n=11) 8周.
- 干预组的参与者每周接受教育,每天准备WFPB餐,通过食物记录监测遵守.
- 患者报告的结果,包括认知功能和疲劳,在基线和8周使用验证的问卷进行了评估.
主要成果:
- 观察到WFPB饮食的高度坚持 (94.3%),饮食脂肪显著减少,纤维摄入量增加.
- 与对照组相比,WFPB组在感知认知功能 (p=0.040) 和情感幸福感 (p=0.016) 中显著改善.
- 在WFPB组内报告了疲劳严重程度和最严重的疲劳显著减少 (分别为p=0.047和p=0.011).
结论:
- 实施显著的饮食变化,如WFPB饮食,对于患有MBC的女性来说是可行的.
- 这种饮食干预可以通过减轻与治疗相关的症状,如认知障碍,疲劳和情绪困扰来改善QOL.
- 需要进一步的研究来证实这些发现,并探索长期影响.
关键词:
乳腺癌 乳腺癌 乳腺癌转移性乳腺癌 转移性乳腺癌营养 营养 营养 营养肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖患者报告的结果.基于植物的植物性食品.人们的生活质量.纯素饮食 纯素饮食是一种纯素饮食.更多相关视频
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