评估平均饮酒量与自杀之间的风险关系:对死亡率相关队列数据的分析
Shannon Lange1,2,3,4, Yachen Zhu5, Charlotte Probst1,2,3,6
1Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, 33 Ursula Franklin Street, Toronto, Ontario, M5S 2S1, Canada.
medRxiv : the preprint server for health sciences
|December 4, 2023
概括
过度饮酒会增加男性的自杀风险. 以前的饮酒对男性和女性来说都会增加自杀风险,这凸显了酒精摄入量和自杀之间的复杂关系. 需要进一步的研究.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 成研究 研究成研究
背景情况:
- 酒精消费是一个重要的公共卫生问题.
- 了解饮酒和自杀之间的联系对于预防工作至关重要.
- 以前的研究表明存在相关性,但细微差别需要进一步调查.
研究的目的:
- 调查每日平均饮酒量与自杀风险之间的关联.
- 根据饮酒状态 (禁酒者,前者,当前者) 和饮酒水平来区分风险.
- 探索酒精与自杀关系中的潜在性别差异.
主要方法:
- 利用了美国国家健康访谈调查 (1997-2018) 的数据,与国家死亡指数 (2019) 相关联.
- 采用了考克斯的比例危险模型和阿伦的附加危险模型来量化相关性.
- 分析按性别分层,并根据教育和婚姻状况等人口因素进行调整.
主要成果:
- 对于男性来说,以前的饮酒和每天40-60克的消费与明显更高的自杀风险 (乘数级) 有关.
- 对于女性来说,在乘法尺度上没有发现显著的关联.
- 在添加量级上,前饮酒增加了男性和女性每10万人年自杀死亡人数.
结论:
- 酒精量与自杀之间的关系是复杂的,并且取决于性别.
- 更高的酒精消费,特别是在男性中,与增加自杀风险有关.
- 建议使用纵向数据进行进一步的研究,以充分阐明这种关系.
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