运动员肠道微生物群的下一代测序:系统性审查
Carlos Sabater1,2, Eduardo Iglesias-Gutiérrez3,4, Lorena Ruiz1,2
1Department of Microbiology and Biochemistry of Dairy Products, Instituto de Productos Lácteos de Asturias-Consejo Superior de Investigaciones Científicas (IPLA-CSIC), Paseo Río Linares s/n, Villaviciosa 33300, Spain.
Microbiome research reports
|December 4, 2023
概括
身体活动塑造了肠道微生物群,影响了体育表现. 通过下一代测序识别的特定细菌及其代谢功能是提高肠道健康和运动能力的关键.
科学领域:
- 微生物学 微生物学
- 运动科学 运动科学 运动科学
- 人类肠道微生物组
背景情况:
- 身体活动通过饮食和微生物相互作用影响肠道微生物群的组成.
- 下一代测序 (NGS) 方法,如枪甲基因组学和16S安普利康测序,可以进行详细的微生物社区分析.
- 了解运动员肠道微生物群对于优化体育表现至关重要.
研究的目的:
- 系统地审查NGS在体育肠道微生物组特征的最新应用.
- 确定肠道微生物群组成概况与体育表现之间的关联.
主要方法:
- 对微生物组研究的系统文献综述.
- 分析使用下一代测序技术的研究 (枪支元基因组学,16S安普利康测序).
主要成果:
- 越来越多的研究趋势侧重于将特定的微生物物种与体育表现联系起来.
- 产生丁酸盐的细菌 (例如, *Faecalibacterium prausnitzii*, *Roseburia hominis*) 与肠道健康和性能有关.
- *Prevotella copri*和*Veillonella atypica*的代谢活动可能会减少肌肉疲劳;在运动员中观察到增强的碳水化合物代谢途径.
结论:
- NGS技术为运动员的肠道微生物组提供了全面的见解.
- 特定的肠道微生物及其代谢功能在体育表现和运动适应方面发挥作用.
- 未来的研究应该专注于个性化的营养策略,以调节肠道微生物组,以改善运动结果.
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