相关实验视频

Updated: Jul 9, 2025

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

在0.35 T磁共振成像引导的线性加速器上进行准确,可重复和几何精确的扩散加权成像

Joseph Weygand¹, Tess Armstrong², John Michael Bryant¹

¹Department of Radiation Oncology, Moffitt Cancer Center, Tampa, FL, USA.

Physics and imaging in radiation oncology

|December 4, 2023

概括

使用回声平面成像 (EPI) 的精确扩散加权成像 (DWI) 现在可以在0.35T的MR-linac (MRL) 上实现. 这项研究证明了用于纵向患者监测的精确表面扩散系数 (ADC) 映射.

科学领域:

磁共振成像是一种磁共振成像技术.
放射治疗物理物理
医学成像技术医学成像技术

背景情况:

扩散加权成像 (DWI) 评估组织细胞性和增殖.
以前的DWI与0.35TMR-linac (MRL) 的整合缺乏定量准确性.
基于回声平面成像 (EPI) 的DWI协议正在为MRL系统开发.

研究的目的:

为了评估0.35T MRL的表面扩散系数 (ADC) 地图的准确性,可重复性和几何精度.
为了证明在MRL上使用DWI进行纵向体内患者成像的潜力.
为了比较0.35T MRL和3.0T诊断扫描仪之间的DWI性能.

主要方法:

在0.35T的MRL上使用基于EPI的DWI协议生成ADC地图.
幻影研究评估了对参考值的准确性和可重复性.
通过将MRL和诊断扫描仪ADC地图与CT图像进行比较,量化了几何扭曲.
在活体中,在两台扫描仪上获得了五名肉瘤患者的ADC地图.

主要成果:

对0.35T的MRL的幻影ADC量化是准确的,在高ADC值中存在小差异.
平均几何扭曲为0.35毫米 (中心) 和0.66毫米 (离中心) 的MRL,而诊断扫描仪的0.85毫米和2.14毫米.
在肉瘤患者的MRL上,预治疗in vivo的平均ADC为910x10^-6mm²/s.

结论:

准确,可重复和几何精确的ADC地图可以在0.35T时使用EPI DWI方法获得.
这些发现支持使用DWI进行长度监测,用于治疗MRL的患者.
基于EPI的DWI显示了增强MRL指导放射治疗的希望.

关键词:

表面扩散系数的明显扩散系数细胞性细胞性细胞性扩散加权成像技术的使用.用MRI指导的放射治疗.

更多相关视频

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging

Published on: December 15, 2014

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

相关概念视频

Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

Imaging Studies I: CT and MRI

Imaging Studies I: CT and MRI

Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...