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癌症新抗原的T细胞识别的结构基础和预测新表位细胞免疫性方面的影响

Roy A Mariuzza1,2, Daichao Wu3, Brian G Pierce1,2

  • 1W.M. Keck Laboratory for Structural Biology, University of Maryland Institute for Bioscience and Biotechnology Research, Rockville, MD, United States.

Frontiers in immunology
|December 4, 2023
PubMed
概括

了解T细胞如何识别癌症新抗原是采用细胞疗法 (ACT) 和癌症疫苗的关键. 结构研究表明,突变可以增强抗原呈现或被T细胞受体 (TCR) 直接检测到.

关键词:
在MHC中,MHC是最重要的.一个T细胞细胞.在TCR中,可以使用TCR.癌症新抗原是一种新抗原.免疫性 免疫性 免疫性免疫疗法 免疫疗法结构 结构 结构 结构

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