人参与肠道微生物群之间的相互作用
Linxian Zhao1, Mingxiu Sui1, Tongbo Zhang1
1Department of General Surgery, The Second Hospital of Jilin University, Changchun, China.
Frontiers in nutrition
|December 4, 2023
概括
人参及其化合物与肠道细菌相互作用,影响健康. 这篇评论探讨了人参如何影响肠道微生物群,以及微生物如何将人参化合物转化为潜在的疗法.
科学领域:
- 微生物学 微生物学
- 药理学 药理学是指药理学的学科.
- 人类健康 人类健康 人类健康
背景情况:
- 肠道微生物群在人类健康中起着至关重要的作用.
- 人参的新陈代谢涉及肠道微生物群,产生生物活性人参酸代谢产物.
- 人参是一种传统的草药,可以通过促进有益细菌和抑制有害细菌来调节肠道菌群.
研究的目的:
- 审查人参和人参酸对肠道微生物群组成的影响.
- 讨论由肠道微生物群介导的金色诺酸的生物转化.
- 总结这些相互作用在相关疾病中的治疗潜力和临床应用.
主要方法:
- 关于人参,人参化物和肠道微生物群的研究文献综述.
- 对人参化合物与胃肠道微生物之间的双向相互作用的研究分析.
- 综合了关于人参对微生物组成和功能影响的研究结果.
主要成果:
- 人参和人参化物显著改变肠道微生物群的组成.
- 肠道微生物群中介于将人参化物代谢成各种生物活性化合物的代谢.
- 人参/人参酸和胃肠道微生物群之间存在复杂的相互作用.
结论:
- 人参及其代谢物对肠道微生物生态有着显著的影响.
- 微生物生物转化是人参化合物的疗效的关键.
- 了解这些相互作用为疾病管理中新的治疗策略提供了潜力.
相关概念视频
What is Monogastric Digestion?
71.2K
The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
71.2K
Anatomy of the Intestines
72.1K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
72.1K
Drug Absorption: Factors Affecting GI Absorption
4.0K
The process of oral drug absorption can be influenced by several factors. Weakly acidic drugs tend to be absorbed more readily from the stomach due to their nonionized state. However, absorption may be less efficient in the upper intestine, where drugs are often ionized. Interestingly, despite the stomach's apparent advantage for drug absorption, its mucous layer can hinder diffusion. Its surface area is also smaller than the intestine's, which can further slow down the absorption rate.
4.0K


