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具有不同基因病理学的双侧丸生殖细胞瘤:一个病例报告
Stivano Rizky Valentino Torry1, Syah Mirsya Warli2,3, Akmal Taher4
1Department of Urology, Faculty of Medicine, Universitas Indonesia - Haji Adam Malik General Hospital, Medan, Indonesia.
Urology case reports
|December 4, 2023
概括
具有不同基因病理学的双侧丸生殖细胞瘤 (TGCT) 是罕见的. 这种病例突出了一个患有纯种子瘤的患者,随后在对侧丸中出现混合的生殖细胞瘤,强调量身定制的治疗和激素替代疗法.
科学领域:
- 在瘤学瘤学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 病理学 病理学 病理学
背景情况:
- 丸癌是20-39岁男性中最常见的固体瘤.
- 丸生殖细胞瘤 (TGCT) 占丸瘤的95%.
- 双边丸瘤很少见,在不到5%的病例中具有相似的组织病理.
研究的目的:
- 报告一种罕见的双侧丸胚芽细胞瘤 (TGCT) 的罕见病例,具有不同的组织学.
- 讨论这样一个罕见的演示的管理影响.
主要方法:
- 一名34岁的男性有纯种子瘤病史,接受了化疗.
- 定子发射断层扫描 (PET) /计算机断层扫描 (CT) 显示了对侧丸异常.
- 手术干预和病理检查证实了对侧丸的混合生殖细胞瘤.
主要成果:
- 该患者在初始治疗半瘤后出现了第二种明显的丸瘤 (混合生殖细胞瘤).
- 第二个瘤包括不成熟的三角瘤,黄囊瘤和胚胎癌.
- 在第二个瘤中,没有发现淋巴血管入侵或精髓干扰.
结论:
- 具有异异本位病理的双边甲时性TGCT异常罕见.
- 治疗策略必须根据二次瘤的特定组织学和阶段量身定制.
- 替代疗法 (TRT) 对于接受双侧耳管切除术的患者至关重要.
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