多学科团队管理是否能改善NSCLC的临床结果? 通过元分析进行系统审查
Gilberto de Castro1, Fabiano Hahn Souza2, Júlia Lima2
1Clinical Oncology, Instituto do Câncer do Estado de São Paulo, São Paulo, Brazil.
JTO clinical and research reports
|December 4, 2023
概括
多学科团队 (MDTs) 改善非小细胞肺癌 (NSCLC) 患者的治疗结果. 以MDT为指导的护理与更长的整体存活率和更好的护理质量有关.
科学领域:
- 在瘤学瘤学.
- 临床研究 临床研究
- 基于证据的医学基于证据的医学.
背景情况:
- 多学科团队 (MDTs) 被认为可以改善癌症治疗结果.
- 然而,关于它们对非小细胞肺癌 (NSCLC) 患者的具体影响,存在有限的可靠文献.
研究的目的:
- 系统地审查和综合现有证据,关于MDTs对NSCLC患者结果的影响.
主要方法:
- 进行了系统的文献搜索,直到2023年2月.
- 两个独立的审稿人进行了研究选择和数据提取.
- 使用随机效应模型的元分析被用于汇集来自22项纳入研究的数据.
主要成果:
- 用MDT治疗的患者的整体存活率显著改善 (HR 0.60,95% CI:0.49-0.75).
- 治疗MDT与更短的治疗时间 (MD 12.20天) 和更高比例的完整分期 (RR 1.36) 相关.
结论:
- 基于MDT的护理显著改善了NSCLC患者的整体存活率.
- 实施MDT提高了护理质量,包括分期和治疗的及时性.
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