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鉴定新型属和子集群分类的真菌菌菌体的鉴定

Laura M O'Connell¹, Colin Buttimer², Francesca Bottacini¹

¹Munster Technological University, Cork T12 P928, Ireland.

Microbiome research reports

|December 4, 2023

概括

这项研究确定了20个新型菌根菌菌体 (MP) 属和13个新子集群,加强了MP分类学和研究和治疗应用集群之间的联系.

科学领域:

病毒学病毒学
生物信息学是一种生物信息学.
微生物基因组学微生物基因组学

背景情况:

菌根菌菌体 (MP) 是感染菌根菌的病毒.
准确的分类 MP 对于理解其多样性和应用至关重要.
目前的分类系统,包括ICTV,NCBI和Actinobacteriophage数据库,需要强大的相关性.

研究的目的:

在真菌菌菌体 (MP) 中识别新的属.
为了验证国际病毒分类委员会 (ICTV) 和国家生物技术信息中心 (NCBI) 分类学和Actinobacteriophage数据库子集群之间的相关性.
为了使国会议员的子集群分配正式化.

主要方法:

使用VIRIDIC进行基因组分配的721个MP基因组的分析.
基于相似度值和单类的基因基因和VICTOR使用新型属的识别.
将已识别的属与Actinobacteriophage数据库子集群进行比较,以测试属子集群假设.

主要成果:

一项初步分析显示,83.3%的子集群支持属子集群假设.
使用VIRIDIC,Gegenees和VICTOR识别了20个新的MP属.
使用的标准还支持创建13个新的子集群,使得对该假设的支持率增加到97.6%.

结论:

在MP属和子集群分类之间存在强有力的联系.
相关的分类学和聚类系统有助于保持最新的MP多样性代表性.
这种改进的分类可以促进研究和治疗目的的菌体的选择.

关键词:

这就是ICTV,ICTV.菌体的菌体受体行动性细菌体的数据库数据库新型属新型属新的子集群新的子集群分类学分类学.

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