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果蔬对脏健康的研究:一项前性随机试验

Heather Kitzman^1,2,3, Aisha H Montgomery¹, Mahbuba Khan¹

¹Baylor Scott and White Health and Wellness Center, Dallas, TX.

Kidney medicine

|December 4, 2023

概括

这项研究发现,给非裔美国人提供水果和蔬菜 (F&Vs) 和指南,使尿液中白蛋白-肌素比率 (ACR) 升高,显著降低了ACR. 这种以社区为基础的方法显示出改善贫困人口脏结果的希望.

科学领域:

基于社区的健康干预措施
科和心血管疾病预防.
营养科学与公共卫生

背景情况:

尿中的白蛋白-肌素比率 (ACR) 升高是慢性病 (CKD) 和心血管疾病 (CVD) 风险的标志物.
以前的研究表明,水果和蔬菜 (F&Vs) 可以降低ACR,并减缓医疗保健系统患者的CKD进展.
低收入的非洲裔美国人社区面临不成比例地更高的CKD率和更差的健康结果.

研究的目的:

评估一个以社区为基础的战略,用于在低收入环境中识别具有高ACR的非洲裔美国人.
评估6个月的F&V协议的有效性,有或没有说明,减少ACR.
测试这个假设,辅助剂的指令增强F&Vs的脏保护作用.

主要方法:

未来的,随机的,平行的2臂研究设计.
142名非洲裔美国成年人ACR>10毫克/克肌素被随机分配给仅接受F&V或带有说明的F&V.
参与者在6个月内每天服用2杯F&V,结果在6周和6个月后进行评估.

主要成果:

71%的参与者在6个月后被保留,高度遵守F&V分布.
与F&V Only组相比,F&V + Cook组在6个月内显示出明显的31%较低的ACR (P=0.02).
组合的F&V摄入量显著增加,生物识别变量在两组都得到改善.

结论:

该研究表明,识别和参与社区居住的有心血管疾病和CKD风险的非洲裔美国人的可行性.
六个月的F&V协议有效改善脏结果和心血管疾病风险因素.
初步证据表明,将指南与F&V提供相结合,对于进一步降低ACR至关重要.

关键词:

非洲裔美国人.专辑蛋白尿症是什么意思心血管疾病心血管疾病慢性脏疾病慢性脏疾病指南指南指南水果和蔬菜的果实和蔬菜

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