血压和10年全因死亡率:来自秘鲁移民研究的发现
Aida Hidalgo-Benites1, Valeria Senosain-Leon1, Rodrigo M Carrillo-Larco2,3
1Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
F1000Research
|December 4, 2023
概括
血压升高显著增加了10年死亡风险. 新的高血压指南 (ACC/AHA 2017) 与JNC-7相比,高血压的患病率翻了一番,影响了患者管理和卫生系统.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 重视高血压对死亡率的长期影响.
- 考虑对高血压诊断截止点提出的变化.
- 评估不同血压分类的死亡风险.
研究的目的:
- 评估高血压水平与10年死亡率之间的关联.
- 为了比较风险,使用预防,检测,评估和治疗高血压联合国家委员会 (JNC-7) 的第七份报告和美国心脏病学会/美国心脏协会 (ACC/AHA) 2017年指南.
- 分析不同高血压定义对死亡结果的影响.
主要方法:
- 秘鲁移民研究的前性队列分析.
- 暴露:根据JNC-7和ACC/AHA 2017指南的血压类别.
- 统计分析:Log-rank测试,Kaplan-Meier和Cox回归模型来估计危险比率 (HR) 和95%信心区间 (95%CI).
主要成果:
- 分析了976名参与者 (平均年龄为60.4岁,52.6%是女性).
- 高血压的患病率从16.0% (JNC-7) 增加到31.3% (ACC/AHA 2017). 在美国,高血压患病率从16.0% (JNC-7) 增加到31.3% (ACC/AHA 2017).
- 血压升高 (前高血压/高血压) 显著增加了10年全因死亡风险 (例如,JNC-7高血压5.1倍).
结论:
- 根据JNC-7和ACC/AHA 2017的定义,血压水平与10年死亡风险的增加有关.
- 与JNC-7相比,ACC/AHA 2017年指南的高血压患病率几乎翻了一番.
- 在采用新的高血压分类门时,平衡患者利益与医疗保健系统能力至关重要.
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