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Updated: Jul 9, 2025

Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions
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空气道上皮细胞和巨细胞触发IL-6-CD95/CD95L轴,并介导COVID-19的初始免疫病理

Thais F C Fraga-Silva1, Ualter G Cipriano2, Marcilio J Fumagalli2

  • 1Department of Biochemistry and Immunology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, Sao Paulo 14049-900, Brazil.

iScience
|December 4, 2023
PubMed
概括

感染SARS-CoV-2会触发气道上皮细胞,激活CD95/CD95L通路. 这一途径驱动巨细胞功能障碍和炎症,表明CD95/CD95L作为严重COVID-19的治疗点.

关键词:
免疫系统的组成部分病毒学 病毒学

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