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Updated: Jul 9, 2025

Through the Looking Glass: Time-lapse Microscopy and Longitudinal Tracking of Single Cells to Study Anti-cancer Therapeutics
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选择性CDK2抑制剂INX-315在固体瘤中诱导细胞周期停止和衰老

Catherine Dietrich1,2, Alec Trub3, Antonio Ahn1,2

  • 1Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.

Cancer discovery
|December 4, 2023
PubMed
概括

一种新药物INX-315可选择性抑制循环素依赖激酶2 (CDK2),显示出治疗CCNE1增强癌症和克服乳腺癌中对CDK4/6抑制剂的耐药性的前景.

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