饮食中的黄类药物摄入量与睡眠障碍与非酒精性脂肪肝疾病风险之间的相互作用:一个横截面研究
Xinxia Yang1, Shitu Zhuo2, Taiyong Fang1
1Department of Gastroenterology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
European journal of gastroenterology & hepatology
|December 4, 2023
概括
饮食中所含的安东素和黄素可能会防止非酒精性脂肪性肝病 (NAFLD). 低摄入量与睡眠问题相结合,协同增加了NAFLD风险.
科学领域:
- 营养科学 营养科学
- 肝病学 肝病学是一种肝病学.
- 睡眠医学 睡眠医学
背景情况:
- 非酒精性脂肪肝 (NAFLD) 是一个日益严重的健康问题.
- 饮食,睡眠和NAFLD风险之间的相互作用尚未完全理解.
- 饮食中的黄类化合物,特别是氨酸和黄类化合物,是强大的抗氧化剂,具有潜在的肝脏保护作用.
研究的目的:
- 调查饮食中的黄酸盐摄入量和睡眠障碍与NAFLD风险之间的相互作用.
- 检查与NAFLD相关的安东素和黄素的特定作用.
- 确定低黄摄入量和睡眠障碍对NAFLD发展是否存在协同作用.
主要方法:
- 从三个国家健康和营养检查调查周期 (2007-2010,2017-2018) 的数据分析.
- 使用美国脂肪肝指数 (≥30) 进行NAFLD诊断.
- 通过验证的问卷来评估睡眠障碍.
- 使用后勤回归,限制立方线和相互作用分析 (相对过剩风险,可归因比例,协同指数) 的统计评估.
主要成果:
- 摄入更多的安东基亚尼丁和黄类药物与NAFLD风险有负相关性.
- 睡眠困难与NAFLD风险增加有关.
- 研究人员观察到,低氨酸/氨酸摄入量和睡眠困难之间在提高NAFLD风险方面存在协同作用,并注意到明显的性别差异.
结论:
- 饮食中摄入的安东素和黄素与NAFLD风险相反相关.
- 睡眠困难与NAFLD风险正面相关.
- 在不充分摄入安东或黄和睡眠障碍之间存在显著的协同效应,强调了对NAFLD发展的综合影响.
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