母亲产前抑郁症状和胎儿在关键快速成长阶段的成长
Lu Zhang1,2, Ping Li1,2,3, Qiaoyue Ge1,2
1Department of Maternal, Child and Adolescent Health, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
JAMA network open
|December 4, 2023
概括
孕产妇抑郁症状与胎儿在关键快速生长阶段 (CRGS) 的生长速度减缓有关. 早期对母亲抑郁症的查对胎儿发育和长期健康至关重要.
科学领域:
- 产科和妇科 产科和妇科
- 围产儿医学 围产儿医学
- 孕产妇心理健康 孕产妇心理健康
背景情况:
- 在临界快速生长阶段 (CRGS) 的胎儿生长,怀孕30-37周,影响未来的健康.
- 已知孕产妇抑郁症状会影响胎儿生长,但它们对CRGS纵向生长的影响不太清楚.
研究的目的:
- 在CRGS期间调查母亲抑郁症状与胎儿生长轨迹之间的关联.
主要方法:
- 一项前性出生队列研究包括2676个母子对象.
- 在怀孕24周时,使用爱丁堡产后抑郁量表 (EPDS) 评估了母亲的抑郁症状.
- 胎儿生长参数 (BPD,FL,AC,EFW) 在妊娠30周和37周使用超声波测量.
- 我们使用线性混合模型来分析这些关联.
主要成果:
- 较高的孕产妇EPDS分数与较慢的胎儿生长率相关联:大腿骨长度 (FL),腹周 (AC) 和估计胎儿体重 (EFW).
- 这些关联在女性胎儿和来自更高社会经济背景的胎儿中更为明显.
- 这项研究分析了2676个母子双的数据.
结论:
- 孕产妇抑郁症状与CRGS期间胎儿生长率降低有关.
- 建议在怀孕期间进行母亲抑郁症的常规查,以支持最佳的胎儿生长和长期健康结果.
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