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酸丁氨酸的合成控制了B细胞淋巴瘤中的瘤性B细胞受体信号传递

Jumpei Omi1, Taiga Kato2, Yohei Yoshihama2

  • 1Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.

The Journal of cell biology
|December 4, 2023
PubMed
概括

向酸胺 (PS) 合成可以抑制B细胞淋巴瘤的生长. 抑制PS合成酶1 (PTDSS1) 破坏癌细胞膜,导致B细胞受体 (BCR) 过活化和细胞死亡,提供了一种新的治疗策略.

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