儿童患者的亚托皮性皮肤炎负担:一项国际横截面研究
Stephan Weidinger1, Eric L Simpson2, Jonathan I Silverberg3
1Department of Dermatology, Allergology and Venereology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
The British journal of dermatology
|December 4, 2023
概括
亚托皮炎 (AD) 显著影响儿童和青少年,中度至重度的病例导致更多的,疼痛,睡眠问题和错过学校的日子. 评估应考虑AD的功能影响.
科学领域:
- 皮肤病学 皮肤病学
- 儿科 儿科 儿科
- 公共卫生 公共卫生
背景情况:
- 儿童年龄组中对亚托皮性皮肤炎 (AD) 负担的大规模国际数据有限.
- 鉴定儿童和青少年阿尔茨海默病的影响对于了解疾病患病率和管理至关重要.
研究的目的:
- 根据疾病严重程度分层的儿科患者的亚托皮肤炎 (AD) 负担的特征.
- 评估AD对儿童和青少年症状,生活质量和日常功能的影响.
主要方法:
- 在18个国家进行了基于网络的横截面调查,涉及被诊断患有AD的儿科患者 (6个月至<18岁).
- 使用经过验证的措施 (面向患者的湿疹测量,患者整体评估) 评估疾病严重程度.
- 结果包括,皮肤疼痛,睡眠障碍,与健康相关的生活质量 (HRQoL),学校缺勤率和无性并发症.
主要成果:
- 该研究调查了7465名患有AD的儿科患者,跨越不同年龄段.
- 与轻度AD患者相比,中度至重度AD患者报告的,皮肤疼痛和睡眠问题显著增加.
- 中度至重度的AD与HRQoL受损和学校缺勤率增加有关;严重的AD比中度的AD带来更大的负担.
- 在所有受访者中,超过92%的人至少有一种阿托皮性并发症.
结论:
- 亚托邦性皮肤炎给儿科患者造成了巨大的负担,特别是那些患有中度至重度疾病的人.
- 调查结果强调需要进行全面评估,评估阿尔茨海默病对儿童和青少年的功能和日常生活的影响.
- 有效的管理策略应该解决除了皮肤症状之外的多方面的AD负担.
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