患有全身性硬化症的患者心房的风险:一项全国性基于人口的研究
Oh Chan Kwon1, Kyungdo Han2, Min-Chan Park1
1Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Rheumatology (Oxford, England)
|December 4, 2023
概括
患有系统性硬化症 (SSc) 的患者患上心房动 (AF) 的风险增加了一倍. 这一发现强调了需要加强对SSc患者的AF监测,因为它对健康有重大影响.
科学领域:
- 心脏病学 心脏病学
- 类风湿病学 类风湿病学
- 流行病学 流行病学
背景情况:
- 心房动 (AF) 是一种普遍存在的心律失常症,具有重大的健康和经济后果.
- 在患有全身性硬化症 (SSc) 的患者中,AF的风险仍然不太清楚.
研究的目的:
- 为了确定SSc患者的AF发病率.
- 为了比较SSc患者与普通人群发生事件AF的风险.
主要方法:
- 使用了韩国国家医疗保险服务数据库 (2010-2019).
- 包括2,519名SSc患者和12,595名匹配的对照.
- 采用多变量Cox比例危险模型来评估AF风险.
主要成果:
- 在SSc患者中,AF发病率为每1000人年3.52,在对照组中为1.68.
- 在SSc患者中,发生性AF的风险显著增加 (调整后HR为2.095).
- 与对照组相比,SSc患者患有AF的风险大约是SSc患者的两倍.
结论:
- 患有SSc的患者面临患上心房动的风险大幅增加.
- 在SSc患者中,由于相关的发病率和死亡率,对发生的AF进行密切监测至关重要.
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