末期病透析患者的家庭炼:随机对照试验的系统审查和元分析
Hongshuang Chen1, Yuxia Guan2, Zijuan Zhou2
1School of Nursing, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100144, China.
Complementary therapies in clinical practice
|December 4, 2023
概括
长期在家进行炼显著改善了透析患者的行走能力和VO2峰值. 然而,它并没有显著影响手握强度,生活质量或生物化学标志物,如CRP.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 运动生理学 运动生理学
- 公共卫生 公共卫生
背景情况:
- 缺乏体力活动会对透析患者的生活质量和功能能力产生负面影响.
- 家庭运动提供了一个低成本的干预措施,但它在这个人群中的有效性需要澄清.
研究的目的:
- 评估家庭运动对透析患者的功能能力,体力,肌肉力量,生化参数和生命质量的影响.
主要方法:
- 在PubMed,Embase,Cochrane图书馆和Web of Science进行了系统的搜索,直到2023年5月.
- 包括12项随机对照试验 (RCT),涉及1008名透析患者.
- 数据提取和偏差风险评估由两个独立的审查员进行,并使用固定或随机效应进行元分析.
主要成果:
- 家庭运动显著改善了身体能力,特别是长期 (3-6个月) 干预的6分钟步行测试结果.
- 接受家庭运动的患者在VO2峰值显著改善.
- 与以中心为基础的炼或常规护理相比,没有观察到手握强度,生活质量,C反应蛋白 (CRP) 或其他生化参数的显著改善.
结论:
- 长期的家庭炼有效提高ESRD透析患者的行走能力和VO2峰值.
- 家庭炼没有显示出对手握力,与健康有关的生活质量或生化标志物的统计学上显著的益处.
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