在低收入和中等收入国家利用新生儿呼吸系统支持:基于注册表的观察性研究
Nora Switchenko1, Vivek Shukla1, Musaku Mwenechanya2
1Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Neonatology
|December 4, 2023
概括
在资源较少的环境中,更多的新生儿比早产婴儿获得呼吸支持. 然而,更高比例的早产婴儿接受了呼吸辅助,尽管风险较低.
科学领域:
- 新生儿护理 新生儿护理
- 全球卫生健康 全球卫生健康
- 呼吸系统的支持呼吸系统的支持
背景情况:
- 新生儿的低氧症需要呼吸辅助.
- 在缺乏资源的环境中,在满期和早产婴儿之间提供呼吸支的差异是未知的.
- 这项研究调查了大型多国出生队列中的呼吸支模式.
研究的目的:
- 为了确定期满或早产婴儿是否在低收入和中等收入国家获得了更多的呼吸支持.
- 为了比较到期和早产新生儿之间的呼吸支的频率和模式.
- 分析不同地理位置的呼吸辅助输送的变化.
主要方法:
- 使用从母亲和新生儿健康登记处前性收集的数据进行观察性研究.
- 纳入标准:2015年至2018年的活产婴儿 (怀孕22-44周,出生体重≥400克).
- 使用强大的波桑回归分析呼吸支 (氧气,CPAP,机械通风) 频率和趋势的分析.
主要成果:
- 总共分析了205,977名婴儿,177,728名终身 (86.3%) 和28,249名早产 (13.7%).
- 更多的预产婴儿 (n=5,108) 获得了呼吸支持,而不是早产婴儿 (n=3,287).
- 接受呼吸辅助的早产婴儿比例 (11.6%) 显著高于成熟婴儿 (2.9%,p<0.001).
结论:
- 长期孕育的婴儿比早产婴儿更频繁地使用呼吸辅助.
- 尽管风险较低,但预产婴儿获得了更多的呼吸支持,这表明在护理方面存在潜在的差异.
- 在各个研究地点观察到呼吸辅助供应的显著差异.
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