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转录因子Aiolos抑制了肠内皮质淋巴细胞的激活

Kentaro Yomogida1,2, Tihana Trsan2, Raki Sudan2

  • 1Department of Pediatrics, University of Colorado Anschutz Medical Campus, Denver, CO, USA.

Nature immunology
|December 4, 2023
PubMed
概括

艾洛斯 (编码为Ikzf3) 调节肠内皮质淋巴细胞 (IEL) 的激活. 它的缺乏会放大IEL效应器功能,增加小鼠对大肠炎的易感性.

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