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亚域动态使非核糖体合成酶中的化学连锁反应成为可能

Xun Sun1,2, Jonas Alfermann3, Hao Li1

  • 1Department of Chemistry, Princeton University, Princeton, NJ, USA.

Nature chemistry
|December 4, 2023
PubMed
概括

非核糖体合成酶 (NRPS) 使用动态基化域 (A域) 来构建复杂的. 这些A域在构造之间切换,使得在生物合成过程中能够连续添加氨基酸.

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