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出生结果和与年龄相关的早期生长模式在肥胖反弹时:马安山出生队列 (MABC) 研究
Jixing Zhou1,2,3,4, Yuzhu Teng1,2,3,4, Shanshan Zhang1,2,3,4
1Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, 230032, China.
BMC public health
|December 4, 2023
概括
早期肥胖反弹 (AR) 与更高的肥胖风险有关. 出生后的结果,如低出生体重和婴儿期快速体重增加,增加了儿童早期AR的风险.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 发育儿科 发育儿科
- 肥胖问题研究研究
背景情况:
- 肥胖反弹 (AR) 的早期发病是未来肥胖的重要预测因素.
- 了解影响早期AR的因素对于制定预防策略至关重要.
研究的目的:
- 研究出生结果和早期身体生长模式与儿童肥胖反弹时间之间的关联.
- 确定与早期AR风险增加相关的关键发展轨迹.
主要方法:
- 利用了2705名儿童的Ma'anshan出生队列 (MABC) 的数据.
- 采用基于组的轨迹建模 (GBTM) 来识别物理生长模式.
- 在生命的头两年分析了体重指数 (BMI),腰围,体脂和快速体重增加 (RWG).
主要成果:
- 72个月前高BMI,腰围和身体脂肪轨迹与早期AR的风险增加有关.
- 低出生体重,早产和小的妊娠年龄增加了早期AR的风险.
- 在前两年,快速体重增加 (RWG) 和特定的BMI轨迹 (低或上升) 也增加了早期AR的风险.
结论:
- 显示高脂肪指标或特定早期生长模式 (RWG,某些BMI轨迹) 的儿童面临更高的早期脂肪反弹的可能性.
- 识别这些早期风险因素对于理解和减轻与儿童肥胖相关的代谢风险至关重要.
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